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Jack Griffin is a Harvard philosophy scholar who loses out on his dream job and goes to work as a high school Advanced Placement biology teacher in his hometown of Toledo, Ohio. He quickly makes it clear he will not be teaching any biology, however, and, realizing he has a room full of overachieving honor roll students at his disposal, decides instead to use the kids to enact revenge on his rival and take the job that is rightfully his. Eager to prove that he is still king of the castle, Principal Durbin struggles to control the force of nature that is Jack Griffin.

When Jack leaves his class unattended, a student injury sets off an official investigation and lands Jack in "teacher jail." An aggressive teacher's union rep sets her sights on Principal Durbin. The students' excitement for a substitute teacher are dashed when they find out it's Helen.

Jack gets into a petty dispute with Marcus, the President of Student Council. Marcus surprisingly refuses to back down and the situation escalates much too far. Stef sells makeup at school as a side business.

Jack puts his students on a new Miles revenge mission. At the same time, Helen, Principal Durbin's upbeat secretary, relentlessly tries to get Jack to make something for the annual bake sale.

Jack reluctantly agrees to go out on the town with Mary, Stef and Michelle. However, his superiority complex proves difficult for the women of Toledo to overcome. Principal Durbin feels threatened when Helen fills in for him on the school's video morning announcements.

When Jack is attracted to a student's mother at a parent-teacher conference, he feigns interest in her son, Colin. A group of parents complain to Principal Durbin when they notice a piece of controversial student art from Mary's class.

Jack receives an offer from Miles' publisher to write a book of feel-good philosophy that could be his ticket out of Toledo. Durbin accidentally sets off an emotional firestorm when he reveals that while Stef chose Mary as her emergency contact, Mary chose Michelle.

Jack finds out his ex-girlfriend Meredith needs a venue for a charity fundraiser and has the perfect place: his student Victor's house. Victor and the other kids are inspired by Jack to party for the first time.

Jack is incensed when his dead mom's former lover shows up and suggests they commemorate her birthday. Jack taps his students to help him retaliate, but the students' hands are already full - of crying robot babies. Stef's kindness toward Dale the janitor sends the wrong signals.

When Jack casually gives Durbin some marriage advice, it backfires, gets Durbin kicked out of the house, and Jack takes him in. The A.P. Bio kids tell Jack if they can get Miles' DNA, they'll learn a little biology while pulling off the ultimate revenge.

When one of Jack's students anonymously reports him for canceling their much-anticipated fetal pig dissection, he sets out to find the snitch. Durbin's chances at Principal of the Year are in jeopardy when the superintendent visits.

Jack successfully convinces Miles that Devin is his illegitimate son. Durbin, Mary, Stef and Michelle clash on the Sadie Hawkins dance theme.

Jack takes interest in a revenge mission on behalf of the A.P. Bio kids. Mary, Stef and Michelle believe they've discovered an otherworldly presence at Whitlock.

With no archrival to combat, Jack sets his sights on a new mission: write the most brilliant philosophy book ever and get out of Toledo for good. Stef and Mary forget a special day for Michele. Helen forgets to order routine maintenance for the copier causing mass hysteria at Whitlock.

Jack is offended when he discovers a local church received a sizable bequest from his dead mother and used it to by a Virgin Mary statue. In an attempt to get revenge, he ropes his students into helping him steal the statue. Meanwhile, Mary, Stef and Principal Durbin attempt to give the right advice to Michelle who is having marital issues at home, but she ends up getting comfort from an unexpected source.

In the hectic thirty minutes that start every day at Whitlock, Jack tries to retrieve his massage chair from Whitlock's intriguing payroll accountant, Lynette. Durbin and Helen prepare for the morning announcements, and Michelle gives a eulogy.

Jack is aghast to learn he didn't make the Top 10 in Toledo's Top 100 bachelors, and Durbin did. Meanwhile, Victor and Eduardo decide it's time to reveal their feelings to their unexpected crushes.

Jack uses Michelle's annual murder mystery party to impress Lynette. Meanwhile, in a moment of desperation, the students break into Whitlock High to steal the A.P. Bio practice exams.

Jack's war with his neighbor reaches a turning point when it threatens to ruin a date with Lynette. And when the school photographer ups his rate, Durbin takes school pictures into his own hands.

Jack is outraged when his old high school bully is hired as a motivational speaker at Whitlock. Meanwhile, Mary, Stef, and Michelle set their own personal goals of female empowerment, unintentionally causing a rift between Helen and Durbin.

When budget cuts threaten to gut Whitlock and put his job in jeopardy, Jack recruits Mary, Stef, and Michelle to take down the Superintendent. Durbin plans an appeal to the heart, while the students plan an appeal to the soul.

After an embarrassing video of himself falling off a stage goes viral, Jack plans a viral video of his own. Meanwhile, Durbin, Helen, and the teachers track down Whitlock's most notorious litterer: the Sugar Daddy.

When he's kicked off his Harvard phone plan, Jack is offered a chance to leapfrog onto Mary's on one condition: He helps her break up with her scuzzy boyfriend. Meanwhile, Anthony becomes Durbin's right-hand man.

After his computer breaks, Jack rallies his class to win the annual Whitlock's Got Talent competition so the prize money can go towards a new laptop. Helen and Durbin put on their best tuxes to host while Mary, Stef and Michelle prepare a hand-bell routine.

It's the most exciting time of the year at Whitlock: Durbin's birthday and Spirit Week. Jack does his best to steer clear of any school spirit as everyone else comes together to take down their hated rivals at Prairie High.

The college fair comes to Whitlock, and Sarika has an offer to Jack: Get her into Harvard, and she'll get his book into the hands of her publisher aunt. Meanwhile, Stef prepares for a visit from a fling, Helen applies to college, and Durbin tries to cement his legacy.

When Jack is disappointed with the popcorn maker he orders, he and the students plot revenge; Helen goes back to school to get her high school degree and chaos ensues in Principal Durbin's office in her absence.

Mr. Pugh plans a field trip for the Toledo chapter of the Ohio Naturalists; when Jack can't write his own book, he agrees to be ghostwrite for popular author Robin Shwank -- only to insert his own chapters into Shwank's book.

Jack accidentally loses a significant amount of money and it falls in the hands of the students; as Principal Durbin and Helen investigate who stole the money, the students and teachers admit to other wrongdoings.

Principal Durbin takes it upon himself to help Jack advance his book with an appearance on Toledo's morning TV show but lets his five minutes of fame get the best of him; the other teachers lead a competition within the Young Entrepreneurs Club.

Jack has Mary drive him to the doctor, but a prank results in him getting the same procedure twice; at school, Durbin and Helen embarrass themselves and the kids compete over class superlative titles.

As the school prepares for winter break, Jack tries to record a lecture on Thoreau's transcendentalism as a way into the University of Wisconsin's philosophy department; frustrated and unable to finish the video, he falls asleep and has nightmares.

Principal Durbin and Helen sweep lockers; Jack finds out that Anthony has been lying about his extracurricular activities; Jack and Lynette follow Anthony to find out what he's really been up to; the search for Stef's baby donor intensifies.

While the rest of the town prepares for the celebration of Toledo's annual Katie Holmes Day, Jack and Marissa plot to ruin the holiday pageant.

A tornado puts the school on lockdown and Helen believes it's coming specifically for her; the kids pass the time by writing fan fiction, "shipping" various combinations of faculty members; Mary, Stef and Michelle devise a plan to escape the school.