With Spooner on board, Ava hopes that her special abilities will help lead them to locate the Aliens spread out on the timeline, which could ultimately lead them to Sara. The Legends soon find themselves tracking an Alien in 1950s San Bernadino and having to figure out what is making the town go on a feeding frenzy. Zari lets Behrad know she is ready to use the Totem, but Behrad isn't ready to share it, causing tension between them. Meanwhile, after crash landing, Sara tries to figure out a plan and runs into none other than Amelia Earhart who could be her ticket home.
An overseas call for help from the daughter of McCall's deceased CIA mentor forces McCall, Mel and Harry to work remotely to aid the conflict journalist as she's pursued by a hit squad in France. Also, Aunt Vi becomes suspicious when McCall skips out on another family night for work.
Lisa makes a shocking college decision, wounding Marge. It leads to a very surprising place.
As the city buzzes with anticipation over a pending execution, Penance grapples with a moral calling at odds with Amalia's plan. With the two women at a crossroads, the Orphans must decide whom to follow.
In therapy, Zoey reflects back on her unexpectedly profound first day working at SPRQPoint.
Grace wakes up with her memory blurred and sees what her world's become years later.
When Sophie must face a foe from her rookie days with The Crows, Ryan, Mary and Luke are also pulled into the villain's game. Meanwhile, the tables turn on Alice when she finds herself in dire circumstances, and Jacob continues to revisit the past.
Brian tries to convince The Griffins that their new adopted cat, Pouncy, is evil.
With Mare forced to take a backseat on the case, Colin presses a local priest about the vague circumstances that prompted his transfer to the parish. Meanwhile, an anonymous call gives Dawn hope that Katie might still be alive.
Assuming the involvement of the Campbell brothers at the Copeland territory shootout, Jackie confronts Grace, who can no longer sidestep her sons' criminal activity. She is forced to make a terrible compromise. Resenting the outcome of a negotiation that he could not take part in, Decourcy finds comfort in the strength of Siobhan, who keeps her head even after tragedy strikes. Jenny insists on helping Maeve, whether or not that means defying Jackie.
Officers Nolan and Bradford hope they can de-escalate a drug war before any innocent lives are lost. Meanwhile, Officer Harper hopes she can get Officer Chen ready to go undercover.
As a nit pandemic sweeps the school, Julia finds herself accused of triggering a second wave.
Ostracised by the other Mums, Julia needs to find a way back into their good books so she throws a nit treatment party that brings everyone's drama (and headlice) into her home.
The party reveals that Anne has some big news, Meg is facing a crisis, and Kevin has committed a terrible crime of passion. As Amanda super spreads the gossip, Liz waits for news about a career move.
Pantalone is planning the heist of the century – a tasty twelve mil in rough cut diamonds. But if you're going to hire a bunch of complete clowns to carry out a robbery, and half of them are planning to double-cross the other half, you've not just got a recipe for disaster, you've actually got the ingredients of a Tarantino Commedia dell'Arte.
When a famous mystery writer dies, Athena, Bobby and the 118 respond to the chaos caused by a city-wide manhunt for buried treasure the author left behind.
Jefferson takes Khalil up on his offer to help. Meanwhile, Lynn finds herself wrestling with what could be the biggest decision of her life. Lastly, Tobias follows through on a hunch.
A recovering Owen becomes the prime suspect in the serial arsonist case. Meanwhile, T.K. and Carlos find themselves in a fiery situation and Tommy gets the surprise of her life.
Shaun struggles with his role as Lea's partner after complications arise with the pregnancy and his instincts as a medical professional kick in. Meanwhile, Dr. Park, Dr. Andrews and Asher disagree on how to address an elderly patient's wishes.
After a devastating betrayal, Barry turns to Timeless Wells for help. Meanwhile, Iris leads Team Citizen down a dangerous road in search of answers, and Cisco confides his biggest fear to Kamilla.
On the day of Nic's baby shower, Billie takes full control to make sure it goes smoothly, but a secret she's been hiding changes everything. Devon and Leela stumble upon an apartment fire, where they assist in getting victims safely to Chastain and Leela gets a chance to prove her skills to Raptor. Meanwhile, Jake and his husband deal with the complications of Sammie's health, as they prepare to become more permanent fixtures in her life, and both Raptor and Rose receive exciting news.
As the Super Friends brave the Phantom Zone to bring Supergirl home, each member of the team is confronted by visions of their worst fear.
Beth navigates her career path. Kate and Toby face unexpected issues. A run in with someone from his past gives Kevin pause.
As the search intensifies for a serial killer on the run, so does Malcolm's tenacity, causing U.S. Marshal Emily Ruiz to kick him off the case. However, Malcolm doesn't back down that easily.
Jeannette and Kate cross paths at the Skylin High takeover of the County Fair, where one is desperate to prove herself and the other to lose herself.
Bishop pulls the trigger on his plan to become the sole king.
When Scarlet gets an alarming call that her sister is missing, Ronald realizes just how twisted his situation has become and must decide his next move. Meanwhile, Cassie, Jenny, Gil and Rosie find themselves in a whole mess of trouble on the ranch, forced to face off against the worst of the Kleinsasser bunch. But this team is tough and even the strongest family trees can fall.
Max implements sweeping changes to hospital sustainability practices. Bloom returns from vacation. Reynolds treats a young patient with deadly heat stroke. Iggy discovers a dangerous situation with a former patient.
Third-year med students begin their rotation in the ED and Maggie keeps a careful eye on one of them. Natalie, whose mom's health takes another decline, tries to cover up how she broke the rules to treat her.
Bravo is tasked with a covert mission to infiltrate a Boko Haram camp, hack its data network and rescue an American hostage.
A fire breaks out at a pet food factory and Casey and Severide help the owner, Pete, get to the bottom of it. The annual garage sale takes place at 51 and everyone is on edge.
As things begin to go haywire at The Claw, a striking stranger appears looking for Nancy, and announces himself as the billionaire Tom Swift. Meanwhile, Ace has issues with the way Nancy insists on handling things with Celia.
After a series of brutal home invasion robberies, Upton immerses herself in the case and finds herself caught between Voight and Halstead.
Ben reunites with a duplicitous foe. Mick and Zeke's dinner party with Jared and his new girlfriend is halted by a calling that ignite the Stone siblings to save the life of one of their own. Olive's friendship with Levi blossoms but is tested.
Walker and Geri are both unsure of their feelings for each other after their kiss and things get very complicated when Hoyt comes home from prison. However, the welcome home party is interrupted when Micki and Walker get word that Clint West is on the run.
Missy's first heartbreak triggers a series of events that lead the Cooper family to the brink.
Hope's suspicion is piqued after Wade shares some startling news with her. To uncover the secrets of a mysterious artifact, Alaric must work with an enemy from his past. After Ethan finds himself in harm's way, MG is forced to make a difficult decision.
Bonnie gains a new outlook on her sobriety after dealing with difficult news. Also, Jill and Andy (Will Sasso) take a big step in their relationship.
Mandy gets jealous after Mike spends time with Ryan at a marketing retreat. Meanwhile, Ed attempts to get Chuck and Joe to see a musical.
After ViCAP links the River Murders to a pharmaceutical company, Clarice seeks help from Julia Lawson, the corporate accountant for the company, who refuses to work with the FBI, and with Clarice specifically. Also, Catherine goes outside for the first time since her rescue from Buffalo Bill, and Ardelia and Agent Garrett connect with a lawyer they hope will take on the Black Coalition's case against the FBI.
Red tries desperately to rescue an old friend at all costs, while Liz and Townsend conduct an interrogation.
It's Fallon and Liam's wedding day and Blake sits her down for a father-daughter talk, but it is not fatherly wedding advice she was expecting, much to her disappointment. Blake continues to try and fulfill his obligations, but as other forces seem to be working against him, he reaches out to Cristal for help. Meanwhile, as things seem to turn to Alexis' favor, Dominique holds another card in her hand. Sam makes a sweeping romantic gesture. Lastly, Adam hosts an unexpected visitor.